Pathology Trivia Question Bank
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Author:
Sepi
Submit Date:
8/15/2007
Question:
What is the most common endocrine anomaly in Langerhan cell Histiocytosis (LCH) and why? Bonus: This endocrine anomaly is part of a triad. Name it and give all three parts.
Answer
:
diabetes insipidus (DI) in LCH is due to infiltration with histiocytes of the pituitary and the suprooptic nuclei that produce ADH. Triad is called Hand-Schuller-Christian disease. 1) proptosis 2) DI 3) lytic bone lesions
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