Pathology Trivia Question Bank
Dermatopathology
Author:
Sepi
Submit Date:
5/21/2007
Question:
Which member of the of the metalloproteinase family, may be more reliable than CD34 in differentiating DFSP from a dermatofibroma?
Answer
:
In a 2002 study Stromelysin 3 (ST3) was shown to positively stain cells in all cases of dermatofibroma (DF) (100%), and no cases (0%)of dermatofibrosarcoma protuberans (DFSP). (J Am Acad Dermatol 2002;46:408-13.)
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