Pathology Trivia Question Bank 
 

Dermatopathology
 
Author: Sepi  
Submit Date: 5/21/2007  
Question: Which member of the of the metalloproteinase family, may be more reliable than CD34 in differentiating DFSP from a dermatofibroma?  
Answer: In a 2002 study Stromelysin 3 (ST3) was shown to positively stain cells in all cases of dermatofibroma (DF) (100%), and no cases (0%)of dermatofibrosarcoma protuberans (DFSP). (J Am Acad Dermatol 2002;46:408-13.)  
     
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