Pathology Trivia Question Bank
Surgical Pathology
Author:
Sepi
Submit Date:
12/12/2006
Question:
What translocation occurs in mucoepidermoid carcinoma?
Answer
:
mucoepidermoid carcinoma is characterized by a t(11;19)(q21;p13) translocation creating the MECT1–MAML2 fusion product. This translocation disrupts the NOTCH signaling pathway. source: Nature Genetics 33, 208 - 213 (2003)
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