Our Division, based in the James Cancer Hospital and OSUWMC Department of Pathology, provides clinical molecular diagnostics for a wide range of cancers and other heritable disorders. Our mission is to provide cutting edge, clinically responsible and cost-effective diagnostics for the patients of Ohio and beyond. Testing is performed at the Polaris Innovation Center (cancer assays) and at the Ackerman campus (inherited disorders).
Molecular Pathology is a medical specialty that seeks to integrate microscopic findings with the genetic changes associated with diseases such as cancer and inflammatory conditions. Goals of this work in cancer patients include more precise diagnostic classification, improved early detection of cancer and providing help in selecting therapies. Another important goal for Molecular Pathology in some cancers is more sensitive detection of low levels of disease to help guide when to continue or restart treatments to help lower the rates of relapse.
The ongoing challenge of Molecular Pathology is to speed the practical application of genomics knowledge emerging from research labs and national initiatives to clinical decision-making in each patient. This involves computer-assisted analysis of sequence data and new methods to display results of genetic tests in the medical record. The Division has initiated a research program to develop new methods for sequence annotation.