About Us:
The Tissue Procurement Shared Resources began in 1975 with
the Ohio State University Comprehensive Cancer Center (OSUCCC)
and was the impetus for the growth of the Human Tissue Resource
Network (HTRN) of The Ohio State University that receives
additional funding from other NCI banking grants, most specifically
the Cooperative Human Tissue Network (CHTN). The TPSR benefits
by the maintenance of the HTRN infrastructure and increased
knowledge of regulations and procedures for procuring tissues
as seen from the national organization. Therefore, the expertise
to manage and operate the OSUCCC's TPSR for these projects
is grouped together to provide economically efficient use
of personnel for the service. The projects mirror one another
but with appropriate separation and definition of expenditure
of funding. The TPSR has received merit descriptors of "outstanding"
in the last two Comprehensive Cancer Center (CCC) competitive renewals (1994 and 1999).
The TPSR procures and provides malignant and normal tissues
from solid tumors to the OSUCCC membership. The TPSR is
part of a large tissue bank network at OSU entitled, "The
Human Tissue Resource Network" that also includes:
the NCI - funded Cooperative Human Tissue Resource Network,
the NCI - funded AIDS and Cancer Specimen Resource, the
Tissue Archive Services, the Research Histology Core Facility
and the Cancer and Leukemia Group B - Pathology Coordinating
Office. The strong institutional and coordinated support
of groups compliments the TPSR to bring together the expertise
and tools to direct tissue resource projects such as to
enhance the support of the OSU CCC. The operation management
and the technical staff provide high quality and consistent
tissue specimens that will likely prove critical to all
six of the OSU CCC scientific programs. This service is
a prospective tissue procurement service for basic science
applications and now includes pre-surgical (biopsy) and
post-surgical collection of specimens for the purpose of
clinical correlative studies by OSU CCC investigators. The
TPSR staff provides quality control of the research specimen
and direct interaction with pathologists and OSU CCC investigators
to better assist in procurement of tissues and to foster
hypothesis - driven cancer research.
Goals:
- To provide a new dedicated tissue procurement service
for laboratory correlative science to be performed in
conjunction with OSUCCC - initiated clinical trials.
- To maintain the current prospective tissue procurement
service providing anonymized tissue specimens for OSUCCC
basic research investigators with quality control validation
of procured tissue.
-
To increase the availability and diversity of tissues
for investigators.
- To improve customer service components to all users of
the TPSR.
- To institute a user compliance check system for accuracy
of tissue requests based on approved IRB applications.
- To provide education to new users on HIPAA authorization
for the use of human specimens in research.
